uk.local.hampshire

Andy Champ < @ > wrote in message
news:osqdnVYHytxJvSfbnZ2dnUVZ8tPinZ2d@ ...
> Paul Nutteing (valid email address in post script ) wrote:
> >
> > The errror rate from peer-reviewed process
> > and publication
> >
/institute/remed/gednap/Information/IJLM_GEDNAP
> >
> > table 1, is 7 percent for crime scene type
> > dna profiles used in the UK
> > and
> > cannot be better than percent due to
> > single kit processing and False homozygosity
> > from peer reviewed article
> > FSI 143 (2004) 47-52
> > /75dbu
> > explained in more detail on my expose someone
> > put in the thread title
> >
>
>
> Paul,
>
> that's a 3-year old journal, and I don't want to pay the 30 bucks. Do
> you have anything more recent, or free, and printed in something like
> Nature or SciAm that I might be able to get hold of?
>
> Andy

Including the electronic-version-only journals are
available in print form via your
local library , Inter-Library loan and
the British Library Document Supply Centre , not explicitly stated on
/services/document/ costing
about 2 pounds per article and 3 weeks turn-around. There is
the same mechanism in the USA (LoC) and Oz
with about the same turn-around.

The salient data from that article
FSI 143 (2004) 47-52
False Homozygosities comparing 2 DNA profiling kits with divided samples
taken from
2055 individuals showing 15 errors comparing SGM plus results to Powerplex
16 results
on 5 loci , so error rate of per cent or 1 in 140.

Person SGM Powerplex
vWA
1 15,15 15,17
2 17,17 17,18
3 15,15 15,18
4 16,16 16,18
5 18,18 18,21
D8S1179
6 12,12 12,16
7 14,14 10,14
8 13,13 13,18
FGA
9 22,25 25,25
10 23,23 21,23
D18S51
11 14,16 14,14
12 10,10 10,18
13 15,16 15,15
So false homozygosity slippage by as much as 8 alleles, 10 to 18.

And one error on D5S818 comparing Profiler and Powerplex
10,11 11,11
10,12 12,12

You can repeat these analyses with the single
kit and it will always show the same (wrong)
locus so wrong profile.

The UK,FSS uses only SGM plus.
I have homozygous loci in my own DNA profile
but that is by SGM+, with another kit one of
them may in fact be heterozygous. So much for
identity via DNA profile. I have 3 homozygous loci
so a 2 percent chance that my reference profile
with the FSS is wrong, just by FH.

ps
What they aren't telling you about DNA profiles
and what Special Branch don't want you to know.
/
or nutteingd in a search engine.

Valid email nutteing@fastmail.....fm (remove 4 of the 5 dots)
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